The common approach for stress testing by American College of Cardiology and American Heart Association indicates the following: Treadmill test: sensitivity 73-90%, specificity 50-74% (Modified Bruce protocol) Nuclear test: sensitivity 81%, specificity 85-95% (Sensitivity is the percentage of people with the condition who are correctly identified by the test as having the condition. Specificity is the percentage of people without the condition are correctly identified by the test as not having the condition). To arrive at the patient's post-test likelihood of disease, interpretation of the stress test result requires integration of the patient's pre-test likelihood with the test's sensitivity and specificity. This approach, first described by Diamond and Forrester in the 1970s, results in an estimate of the patient's post-test likelihood of disease. The value of stress tests has always been recognized as limited in assessing heart disease such as atherosclerosis, a c...
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